Methyl-Plex B is a comprehensive formula designed to support healthy homocysteine levels and optimal methylation. The 5-MTHF in this formula, Quatrefolic, is the most biologically active form of folate, allowing rapid uptake into the bloodstream.* The 5-MTHF in this formula is also known as the "L" form of 5-MTHF since it is the reduced form of folate. B vitamins are provided in their active forms to support enhanced methylation and cardiovascular health.