Functions as a donor of methyl groups in over 100 different reactions catalyzed by methyltransferase enzymes, as well as a precursor molecule for glutathione and polyamine synthesis

Supports positive mood and cognitive function

• In a meta-analysis involving 25 controlled trials and 791 individuals, SAMe offered statistically significant support for positive mood
• Promotes healthy protein turnover to support healthy CNS function
• Maintains healthy phospholipid methylation to support phosphatidylcholine production and cellular membrane integrity and fluidity
• Supports neurotransmitter monoamine synthesis and function, including dopamine and serotonin, through SAMe-dependent methylation reactions

Promotes liver function by supporting glutathione production

• Clinical trials indicate that SAMe administration enhances glutathione production in hepatic tissue and red blood cells

Enhances joint comfort by supporting proteoglycan synthesis, as well as helping to stabilize and protect proteoglycans

• In a 16-week randomized, double-blind, placebo-controlled trial involving 56 subjects, SAMe offered statistically significant support for joint comfort

Maintains healthy cell growth and cytokine balance by supporting healthy polyamine production. Provides 200 mg SAMe per capsule to support positive mood, cell membrane fluidity, neurotransmitter synthesis, glutathione production, joint comfort and healthy cell growth.