Combines phytonutrients and bile salts with essential vitamins and minerals to provide comprehensive nutritional support for hepatobiliary function.  Nutrients, such as choline and methionine, act as methyl donors in hepatic transmethylation reactions, including the conversion of homocysteine to methionine.  Vitamins B-6, B-12 and folic acid are required as cofactors for these conversions.  Silymarin, which has been researched for its antioxidant effects, has also been reported to act as a methyl donor.