The unique characteristic of modified citrus pectin versus other pectins is that it has a low molecular weight. This allows it to pass through the intestinal barrier and work systemically where it binds to low levels of heavy metals present from common, mild environmental exposure and facilitates their excretion. A recent study indicates that modified citrus pectin promotes healthy urinary excretion of common, mild environmental exposures of mercury, arsenic, cadmium, lead and tin without altering excretion of other minerals, including calcium, magnesium, iron, copper and selenium. Chlorella has a long history of traditional use in supporting the body's natural detoxification process, particularly helping to regulate common heavy metal exposure and distribution in tissues. Sulforaphane, from broccoli sprout concentrate, promotes Nrf2-mediated signaling. Nrf2 controls the expression of numerous genes responsible for detoxification and protection against oxidative stress. As part of a cysteine-rich metal-binding protein, zinc exhibits similar properties. Studies suggest that selenium binds to mercury, potentially reducing the biological availability of mercury, while n-acetyl-l-cysteine (NAC) promotes urinary excretion of methylmercury. In addition, NAC provides important support for the liver by enhancing glutathione concentration. l-Methionine also promotes glutathione production and encourages phase II detoxification pathways in the liver. Alpha lipoic acid promotes the biliary excretion of inorganic mercury and may help regulate heavy metal induced oxidative stress.*