Glucosamine is combined with sulfur-containing methylsulfonylmethane (MSM), ginger and curcumin to provide an enhanced spectrum of nutrients for optimal cartilage matrix composition, connective tissue strength, and joint comfort.

Cartilage Composition: Glucosamine sulfate and MSM provide intrinsic compounds essential for healthy cartilage formation, including glycosaminoglycans and elemental sulfur, respectively. Studies have indicated that glucosamine has the ability to support healthy cartilage integrity, in part by maintaining healthy matrix metalloproteinase (MMP) enzyme activity. In addition, an important role of sulfur from MSM is to enhance the structure and integrity of proteoglycans.

Joint Comfort: A recent randomized, double blind, placebo-controlled trial revealed that MSM promotes joint comfort and function. MSM has also been attributed with enhancing healthy immune cell activity, thereby supporting tissues surrounding the joints. Additionally, ginger promotes healthy prostaglandin and leukotriene biosynthesis, while curcumin helps maintain healthy neutrophil function and scavenges free radicals such as nitric oxide.

OptiMSM® is a registered trademark of Bergstrom Nutrition.