Glucosamine HCl and chondroitin sulfate are combined with sulfur-containing methylsulfonylmethane (MSM) to provide an enhanced spectrum of nutrients for optimal cartilage matrix composition, connective tissue strength, and joint comfort.

Cartilage Composition: Glucosamine promotes the synthesis of the glycosaminoglycan chondroitin sulfate. Chondroitin sulfate is responsible for building the ground substance of cartilage, molecules known as proteoglycans. Studies have indicated that glucosamine HCl has the ability to support healthy cartilage integrity, in part by maintaining healthy matrix metalloproteinase (MMP) enzyme activity. In addition, an important role of sulfur from MSM is to enhance the structure and integrity of proteoglycans.

Joint Motility and Function: Several studies indicate that the combination of glucosamine HCl and chondroitin sulfate has positive effects on joint mobility and comfort. Additionally, a recent randomized, double blind, placebocontrolled trial revealed that MSM also promotes joint comfort and function.

OptiMSM® is a registered trademark of Bergstrom Nutrition.