Glucosamine and chondroitin sulfate are combined with manganese to provide support for optimal cartilage matrix composition, connective tissue strength, and joint comfort

Cartilage Composition: Glucosamine promotes the synthesis of the glycosaminoglycan chondroitin sulfate. Chondroitin sulfate is responsible for building the ground substance of cartilage, molecules known as proteoglycans. Studies have indicated that glucosamine HCl has the ability to support healthy cartilage integrity, in part by maintaining healthy matrix metalloproteinase (MMP) enzyme activity. The trace mineral manganese plays a key role in supporting glycosaminoglycan and mucopolysaccharide production and encourages the antioxidant activity of superoxide dismutase. Ascorbate is a vital nutrient for proper collagen formation and also serves as an antioxidant.

Joint Motility and Function: Several studies suggest that the combination of glucosamine HCl, chondroitin sulfate and manganese ascorbate may provide particular support for joint mobility and comfort.